The Platypus® AV Fistula Needle Guard sets the standard in needle safety for apheresis and hemodialysis procedures, offering unparalleled dual shield protection. Designed to reduce needlestick injuries, which affect over 385,000 US healthcare workers annually, this guard immediately encloses the needle upon withdrawal, safeguarding against biohazard exposure and accidental needle movement. The unique secondary locking feature of the Platypus® Needle Guard not only shields but also fully encases the needle and any residual blood drops, minimizing exposure risks further and allowing for safe disposal. Its sleek, low-profile design facilitates effortless withdrawal, integrating seamlessly into existing medical procedures with minimal training required. The guard can be pre-attached to needle tubing before or during procedures or even during the manufacturing of procedure kits, enhancing flexibility and ease of use. First introduced in 1998, the Platypus® Needle Guard continues to be a critical component in enhancing procedural safety, making it an essential tool for blood banks and donation centers focused on best practices in needle safety.